Interaction of CTX-M-15 enzyme with cefotaxime: a molecular modelling and docking study
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منابع مشابه
Interaction of CTXM15 enzyme with cefotaxime: a molecular modelling and docking study
Extended-spectrum β-lactamases (ESBLs) are the bacterial enzymes that make them resistant to advanced-generation cephalosporins. CTXM enzymes (the most prevalent ESBL-type) target cefotaxime. Aims of the study were: Modelling of CTX-M enzyme from bla(CTX-M) sequences of clinical Escherichia coli isolatesDocking of cefotaxime with modelled CTX-M enzymes to identify amino acid residues crucial to...
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This is the first report regarding the detection of blaCTX-M genes encoding CTX-M-1, CTX-M-15, and CTX-M-2 cefotaximases in clinical isolates of enterobacteria collected in hospitals in Bogotá, Colombia. During a period of 4 months in 2005, 117 isolates of enterobacteria having extended spectrum beta-lactamase (ESBL) phenotype were collected from nine third-level hospitals in Bogotá, Colombia. ...
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ژورنال
عنوان ژورنال: Bioinformation
سال: 2010
ISSN: 0973-8894,0973-2063
DOI: 10.6026/97320630004468